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Dofetilide and Cimetidine Interaction: Why This Combination Can Be Deadly
Medications
By Caspian Drummond
1 Feb, 2026

Dofetilide and Cimetidine Interaction: Why This Combination Can Be Deadly

Dofetilide and cimetidine together can cause life-threatening heart rhythms. Learn why this interaction is strictly contraindicated, how it works, and what safer alternatives exist.

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