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Obesity Pathophysiology: How Appetite and Metabolism Go Wrong
Health Conditions
By Caspian Drummond
12 Feb, 2026

Obesity Pathophysiology: How Appetite and Metabolism Go Wrong

Obesity isn't about willpower - it's a biological malfunction where hunger signals go haywire and metabolism slows. Learn how leptin resistance, brain circuits, and hormones like ghrelin and insulin trap the body in a cycle of overeating.

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