Fertility Medication Comparison: Find the Right Treatment for You

When you're trying to conceive, fertility medication, drugs designed to stimulate ovulation or improve reproductive hormone balance. Also known as ovulation induction agents, these medications are often the first step in treating infertility. Not all fertility drugs work the same way, and choosing the wrong one can mean wasted time, unnecessary side effects, or higher costs. The right medication depends on your diagnosis, age, medical history, and how your body responds.

Three main types of fertility medications dominate the landscape: clomiphene citrate, an oral pill that tricks the brain into producing more follicle-stimulating hormone, letrozole, a breast cancer drug repurposed for fertility that often outperforms clomiphene in women with PCOS, and gonadotropins, injectable hormones that directly stimulate the ovaries. Each has different success rates, risks, and price tags. Clomiphene is cheap and widely used, but letrozole has shown better pregnancy rates in recent studies—especially for women with polycystic ovary syndrome. Gonadotropins work faster and are stronger, but they’re more expensive and carry a higher risk of multiple pregnancies.

It’s not just about which drug works best—it’s about matching the drug to your body. Some women respond well to pills, others need injections. Some need just one cycle, others need several tries. Side effects like mood swings, bloating, or ovarian hyperstimulation aren’t the same for everyone. And while cost matters, skipping the right medication to save money can cost more in the long run through repeated cycles or missed opportunities.

Below, you’ll find real comparisons of fertility drugs based on clinical data, patient experiences, and cost breakdowns. You’ll see how clomiphene stacks up against letrozole, what gonadotropins really cost out-of-pocket, and which options are safest for women with thyroid issues or insulin resistance. These aren’t generic lists—they’re practical, side-by-side reviews from people who’ve been there. Whether you’re just starting out or have tried a few rounds already, this collection gives you the facts to make a smarter, more confident choice.